2721 - Gout #2

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Campaign ID: 3309
Category: Clinical Trials
Payout: $30.00
Description:
LIVE GEOS (ALWAYS UP TO DATE) https://partners.subjectwell.com/publishers/geos_report/c8c8526c-2e61-44ab-9c82-e8c54d82c67b Age Range: 18+ Gender: Any Study Description: Periodically, individuals with gout have a sudden onset of symptoms, or a “flare,” characterized by severe pain, joint swelling, redness, and/or warmth in one or more joints. You have been referred here to be considered for participation in a clinical research study because you have gout or you have experienced symptoms of a gout flare in the past. Gout flares often start suddenly at night, and the intense pain may be bad enough to wake you up. Gout flares usually occur in one joint and can be triggered by certain foods or medications, alcohol intake, physical trauma, or certain illnesses. This research study is looking to see if an investigational drug (dapansutrile) can potentially reduce inflammation, joint pain, and other joint symptoms (such as tenderness and swelling) and if it is safe in adults currently experiencing a gout flare. You may be eligible to participate in the study immediately if you are currently having active symptoms of a gout flare, including warm, swollen, and/or painful joints (most commonly in the big toe). Even if you are not currently experiencing symptoms of a gout flare, you may still qualify to join a Virtual Waiting Room until the next time you develop active symptoms of a flare. Qualifications: - Must have gout diagnosis - Cannot be currently suffering from any other type of inflammatory arthritis or joint pain (instead of, or in addition to, gout), including: - Rheumatoid Arthritis - Lyme Disease - Lupus - Psoriatic Arthritis - Cannot have tophi associated with your gout (Tophi are visible bumps under the skin made of hardened deposits of uric acid crystals that develop around joints.)

3001 - Treatment Resistant Depression #2

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Campaign ID: 3308
Category: Clinical Trials
Payout: $65.00
Description:
Live Geos: https://partners.subjectwell.com/publishers/geos_report/bc51d5ad-1594-4e35-b982-4130bc5baadb *COPY AND CREATIVE MUST BE SUBMITTED TO AFFILIATES@SUBJECTWELL.COM PRIOR TO GOING LIVE* Ages: 18+ Gender: All Study Description: The purpose of this study is to see whether an investigational drug can be used to treat depression that has not responded to other antidepressant therapies. Many people who receive antidepressant treatment for their depression do not get an adequate response to the medicines they are taking. If someone has taken, or is currently taking, two or more antidepressants that are not working, this is sometimes referred to as treatment-resistant depression or TRD. The investigational drug in this study is a synthetic (man-made) form of psilocybin, also known as magic mushrooms. The use of this study drug is legal for research purposes. You may qualify to participate if you are currently experiencing a depressive episode that is not being helped with medication. If enrolled, you will be randomly selected to receive one of 3 doses of the investigational study drug with the support of a specially trained therapist. The dosing session will last approximately 6 to 8 hours and will be video, and audio recorded. You will be required to attend several screening visits to determine your eligibility for the study. Your total participation in the study will last up to approximately 1 year with multiple follow-up appointments after your dosing session. Please note, some of the visits during the study can be conducted remotely. There are up to two re-treatment opportunities throughout the study. One is an open label period of the study where you are guaranteed to receive the highest dose of the investigational study drug, if you are eligible. Study assessments will include collections of blood and urine samples, physical exams, and questionnaires on your experience and mental health. The research site conducting the study will be able to provide you with more information about the requirements for enrollment. Reimbursement for reasonable, out-of-pocket expenses and travel may be available to qualified individuals. Top DQs: - Current depression episode of depression has lasted 6 months + - Must have tried two or more anti-depressant medications to treat this current episode of depression - Cannot also be diagnosed with schizophrenia, schizoaffective disorder/Schizophreniform Disorder, Bipolar Disorder, or Borderline Personality Disorder

2994 - High Cardiovascular Risk (Ages 50+)

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Campaign ID: 3307
Category: Clinical Trials
Payout: $40.00
Description:
Live Geos: https://partners.subjectwell.com/publishers/geos_report/d59c801b-a2be-45f8-b725-fa60c43559a7 **ALL COPY AND CREATIVE MUST BE SUBMITTED TO AFFILIATES@SUBJECTWELL.COM PRIOR TO SETTING LIVE FOR COMPLIANCE** Ages: 18+ Gender: Any Study Description: This study is testing an oral investigational medication to reduce the risk of cardiovascular events. Participants will receive the investigational medication or a placebo for approximately 6 years. Additional procedures include vital signs, blood and laboratory testing. Total participation will last approximately 6 years and 3 months and would include 14 doctor’s visits throughout the study. Eligibility for the study will be determined by the study doctor following one or more in-person screening visits to the clinic. Trial-related procedures and study medication will be provided at no cost. Qualifications/Highest DQs: - Must be currently on a statin medication such as: Atorvastatin (Caduet, Lipitor), Rosuvastatin (Crestor), Simvastatin (Vytorin, Zocor), Pravastatin (Pravachol), Lovastatin (Altoprev), Fluvastatin (Lescol), Pitavastatin (Livalo)

3064 - Cirrhosis

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Campaign ID: 3306
Category: Clinical Trials
Payout: $40.00
Description:
Live Geos: https://partners.subjectwell.com/publishers/geos_report/c090f6db-b690-4e1a-a639-a826dcccdb2e **ALL COPY AND CREATIVE MUST BE SUBMITTED TO AFFILIATES@SUBJECTWELL.COM PRIOR TO SETTING LIVE FOR COMPLIANCE** Ages: 18-80 Gender: Any Study Description: This study is testing an investigational injectable medication compared to a placebo for the treatment of Cirrhosis caused by NASH. Participants will receive the study medication or placebo for approximately 6.5 months. Additional procedures include Magnetic Resonance Imaging (MRIs), FibroScans, physical examinations and laboratory assessments. Total participation will last approximately 10 months and would include 10 doctor’s visits throughout the study. Eligibility for the study will be determined by the study doctor following two in-person screening visits to the clinic. Trial-related procedures and study medication will be provided at no cost. Qualifications/Highest DQs: - Must have been told by a physician that you have cirrhosis of the liver and confirmed by a liver biopsy

2948 - High Blood Pressure

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Campaign ID: 3305
Category: Clinical Trials
Payout: $45.00
Description:
Live Geos: https://partners.subjectwell.com/publishers/geos_report/a4a6a7f8-83e8-45f7-bf9b-359fac895ea0 *ALL COPY AND CREATIVE MUST BE SUBMITTED TO AFFILIATES@SUBJECTWELL.COM PRIOR TO SETTING LIVE FOR APPROVAL** Gender: All Ages: 18+ Study Description: This study is testing an investigational oral medication for high blood pressure. Participants will take the study medication or placebo, which looks like the investigational medication but does not contain the active ingredient being tested, once a day for approximately 3 months. Additional procedures include physical examinations, blood tests, repeated blood pressure assessments, and electrocardiograms. Total participation will last approximately 5 months and would include 11 doctor’s visits throughout the study. Eligibility for the study will be determined by the study doctor following one or more in-person screening visits to the clinic. Study related procedures and study medication will be provided at no cost for the duration of the study. Highest DQs: - Must be taking at least 3 blood pressure medications currently - One of your blood pressure medications can be a diuretic (water pill)

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